Gene interactions and pathways from curated databases and text-mining
Cell cycle (Georgetown, Tex.) 2007, PMID: 17314511

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

Koch, Heike B; Zhang, Ru; Verdoodt, Berlinda; Bailey, Aaron; Zhang, Chang-Dong; Yates, John R; Menssen, Antje; Hermeking, Heiko

The c-MYC oncogene encodes a transcription factor, which is sufficient and necessary for the induction of cellular proliferation. However, the c-MYC protein is a relatively weak transactivator suggesting that it may have other functions. To identify protein interactors which may reveal new functions or represent regulators of c-MYC we systematically identified proteins associated with c-MYC in vivo using a proteomic approach. We combined tandem affinity purification (TAP) with the mass spectral multidimensional protein identification technology (MudPIT). Thereby, 221 c-MYC-associated proteins were identified. Among them were 17 previously known c-MYC-interactors. Selected new c-MYC-associated proteins (DBC-1, FBX29, KU70, MCM7, Mi2-beta/CHD4, RNA Pol II, RFC2, RFC3, SV40 Large T Antigen, TCP1alpha, U5-116kD, ZNF281) were confirmed independently. For association with MCM7, SV40 Large T Antigen and DBC-1 the functionally important MYC-box II region was required, whereas FBX29 and Mi2-beta interacted via MYC-box II and the BR-HLH-LZ motif. In addition, regulators of c-MYC activity were identified: ectopic expression of FBX29, an E3 ubiquitin ligase, decreased c-MYC protein levels and inhibited c-MYC transactivation, whereas knock-down of FBX29 elevated the concentration of c-MYC. Furthermore, sucrose gradient analysis demonstrated that c-MYC is present in numerous complexes with varying size and composition, which may accommodate the large number of new c-MYC-associated proteins identified here and mediate the diverse functions of c-MYC. Our results suggest that c-MYC, besides acting as a mitogenic transcription factor, regulates cellular proliferation by direct association with protein complexes involved in multiple synthetic processes required for cell division, as for example DNA-replication/repair and RNA-processing. Furthermore, this first comprehensive description of the c-MYC-associated sub-proteome will facilitate further studies aimed to elucidate the biology of c-MYC.

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Text Mining Data

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Manually curated Databases

  • IRef Biogrid Interaction: MYC — MARS (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — XPO5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NOP56 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TRRAP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MAX (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MAX (direct interaction, fluorescent resonance energy transfer)
  • IRef Biogrid Interaction: CCAR2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCAR2 — MYC (direct interaction, two hybrid)
  • IRef Biogrid Interaction: IQGAP2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: POLR2B — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — GTF2I (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MMS19 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FBXW8 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FBXW8 — MYC (direct interaction, two hybrid)
  • IRef Biogrid Interaction: MYBBP1A — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RAF1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GTF3C3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GTF3C1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BCR — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HUWE1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MSH2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HDAC1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — POLR2A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NCL — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMA2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSPH1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IKBKAP — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLC25A1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMB4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — RNGTT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GTF3C4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — RPP30 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF281 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF281 — MYC (direct interaction, two hybrid)
  • IRef Biogrid Interaction: PSMC3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — HIST1H2BL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NDUFA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCT4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — IGF2BP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS34 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — RPN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ALDH18A1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSMD2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AKAP8 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — OAT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — HNRNPF (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PLOD3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBE3C — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMD3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NUP153 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLIT2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ERCC3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DNAJA2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CEPT1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCT8 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TUBGCP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMA5 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KPNA4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMC6 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARL1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TOP2A — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DHX15 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MOGS (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DPM1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARF4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CSE1L — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — XPO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSMA4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AASS — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: XPOT — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DIMT1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NDUFS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MSH3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUCLG1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLC25A13 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — YWHAB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — ASS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — GSG2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMA7 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — LONP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO7 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SHOC2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KPNB1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBG1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WDR77 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RANBP2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HNRNPK — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PELO — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — HSPB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MYO5C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: C1QBP — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: XRCC5 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IRS4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDUFS3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DDX52 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FBL — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KPNA2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IDH3B — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDUFA8 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MYO9A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — YWHAE (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMARCA5 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — CCT5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PTGES2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — HSPD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HNRNPA0 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — SQSTM1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS22 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMB1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AKAP8L — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NEK9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HADHB — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — EIF3E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHTF18 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YWHAQ — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PTPN14 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMB3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PLK1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — SKP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ABI3BP — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — CYR61 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RNH1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACOT8 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SQRDL — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DDX1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SARS — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: POLD1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GTF3C2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — ATP5C1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RFC3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: XRCC6 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ILVBL — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IDH3A — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: COPG2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSMA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — HIGD1A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSME4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EIF3I — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EEF1G — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: U2SURP — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLC25A12 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PCBP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DYNC1H1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LMNA — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO13 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — RFC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MAPKAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: XRN1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EIF4A1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — GANAB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TTC27 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — IRAK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ETFA — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GCDH — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IDH3G — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FANCD2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PPT1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EIF4ENIF1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSMB5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TRMT1L (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PPP6C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPN2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TCP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — CCT6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PPP1CA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — IGF2BP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRKDC — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — UBR2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — NONO (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — IQGAP3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — CCT3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SPTLC1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMC2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCT2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PSMA3 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — PSMC4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — SSR4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DNAJB6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — SLC25A11 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ALDH1B1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — P4HA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TMPO (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDUFS2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MYO9B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — ATP5J2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — RFC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — DNAJA3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GCN1L1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SNRNP200 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NUP133 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — FBXW7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — POLE (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — TOP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHD4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — SMC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMC4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMARCC1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA4A — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — EFTUD2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — ARHGEF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRPF6 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DDX20 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO4 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LRPPRC — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TRIM28 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HDAC2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HELLS — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF121 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MSH6 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MCM7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — MCM7 (direct interaction, two hybrid)
  • IRef Biogrid Interaction: MYC — IPO9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: COPG1 — MYC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYC — ACTL6A (physical association, affinity chromatography technology)
  • IRef Intact Interaction: MYC — CCAR2 (physical association, anti tag coimmunoprecipitation)
  • IRef Intact Interaction: MYC — CCAR2 (physical association, anti bait coimmunoprecipitation)
  • IRef Intact Interaction: MYC — CCAR2 (physical association, two hybrid)
  • IRef Intact Interaction: MYC — FBXW8 (physical association, anti tag coimmunoprecipitation)
  • IRef Intact Interaction: MYC — FBXW8 (physical association, two hybrid)
  • IRef Intact Interaction: Complex of MYC-MCM7-CCAR2-EFTUD2-XRCC6 (association, anti tag coimmunoprecipitation)
  • IRef Intact Interaction: Complex of 222 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: MYC — CHD4 (physical association, anti tag coimmunoprecipitation)
  • IRef Intact Interaction: Complex of 13 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: EFTUD2 — MYC (physical association, cosedimentation through density gradient)
  • IRef Intact Interaction: MYC — ZNF121 (physical association, two hybrid)
  • IRef Intact Interaction: Complex of 13 proteins (physical association, cosedimentation through density gradient)
  • IRef Intact Interaction: MYC — MCM7 (physical association, anti tag coimmunoprecipitation)
  • IRef Intact Interaction: MYC — MCM7 (physical association, anti bait coimmunoprecipitation)
  • IRef Intact Interaction: MYC — MCM7 (physical association, two hybrid)
In total, 24091 gene pairs are associated to this article in curated databases